Organic nanomedicine containing nonlinear optical chromophores for ultrastable photo-to-heat converting theranostics in the near-infrared window
نویسندگان
چکیده
Organic molecules that are active in the near-infrared (NIR) bio-window for photo-to-heat energy-converting theranostics have attracted much attention cancer therapy. However, current organic NIR-absorbing still suffering from inefficient non-radiative decay or serious photobleaching under light irradiation. Herein, we design a convenient strategy to load new kind of nonlinear optical (NLO) chromophore FTC-3f with biocompatible polymer, methoxy poly(ethylene glycol)-poly(lactideco-glycolide) (mPEG-PLGA). The resulted FTC-3f/PLGA nanoparticles showed excellent stability, high photothermal conversion efficiency (∼51.11%) and good photoacoustic performance. Moreover, vitro anticancer experiments demonstrated possess PTT (photothermal therapy) NIR laser This work thus provides an insight into exploration versatile toward future practical application.
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ژورنال
عنوان ژورنال: Dyes and Pigments
سال: 2023
ISSN: ['1873-3743', '0143-7208']
DOI: https://doi.org/10.1016/j.dyepig.2022.110962